ref

content/analysis_13n-nh3.html

 ---
 title: Analysis of [N-13]ammonia
 author: Vesa Oikonen, Chunlei Han
-updated_at: 2023-05-10
+updated_at: 2023-09-28
 created_at: 2007-11-21
 tags:
   - Perfusion
@@ -275,7 +275,10 @@ This method has been used in rat studies in a myocardial infarction model
 In later rat [<sup>13</sup>N]NH<sub>4</sub><sup>+</sup> studies only the first 2 min has been 
 used in the analysis to minimize the effect of circulating metabolites
 (Ismail et al., <a href="https://doi.org/10.1186/s13550-016-0209-4">2016</a> and 
-<a href="https://doi.org/10.1371/journal.pone.0177451">2017</a>).</p>
+<a href="https://doi.org/10.1371/journal.pone.0177451">2017</a>).
+With long axial field of view PET systems the RBF can be quantified from data acquired during 
+routine clinical myocardial perfusion PET/CT
+(<a href="https://doi.org/10.1161/CIRCIMAGING.123.015324">Brown et al., 2023</a>).</p>
 
 <p><a href="https://doi.org/10.1038/ki.1993.340">Nitzsche et al (1993)</a> simplified the analysis
 further by using <a href="./model_mtga.html#patlak">Patlak plot</a> to estimate RBF, and validated

content/target_tau-protein.html

 ---
 title: Tau proteins
 author: Vesa Oikonen
-updated_at: 2023-08-17
+updated_at: 2023-09-28
 created_at: 2015-08-17
 tags:
   - Tau protein
@@ -202,7 +202,8 @@ high affinity (∼1.5 nM) and selectivity.
 <a href="./target_microtubules.html#MPC-6827">[<sup>11</sup>C]MPC-6827</a> is a promising
 PET radioligand for MT imaging 
 (<a href="https://doi.org/10.1021/acs.jmedchem.8b00028">Kumar et al., 2018</a>;
-<a href="https://doi.org/10.3390/molecules25102289">Damuka et al., 2020</a>).</p>
+<a href="https://doi.org/10.3390/molecules25102289">Damuka et al., 2020</a>;
+<a href="https://doi.org/10.1021/acschemneuro.3c00527">Bhoopal et al., 2023</a>).</p>
 
 
 <br>