diff --git a/content/analysis_13n-nh3.html b/content/analysis_13n-nh3.html index 8c5f0ad64a011d2ff5c3131e0d4d1fd553aef623..4f431be2fcfe30643668456cf478db53bbe3d679 100644 --- a/content/analysis_13n-nh3.html +++ b/content/analysis_13n-nh3.html @@ -1,7 +1,7 @@ --- title: Analysis of [N-13]ammonia author: Vesa Oikonen, Chunlei Han -updated_at: 2023-05-10 +updated_at: 2023-09-28 created_at: 2007-11-21 tags: - Perfusion @@ -275,7 +275,10 @@ This method has been used in rat studies in a myocardial infarction model In later rat [<sup>13</sup>N]NH<sub>4</sub><sup>+</sup> studies only the first 2 min has been used in the analysis to minimize the effect of circulating metabolites (Ismail et al., <a href="https://doi.org/10.1186/s13550-016-0209-4">2016</a> and -<a href="https://doi.org/10.1371/journal.pone.0177451">2017</a>).</p> +<a href="https://doi.org/10.1371/journal.pone.0177451">2017</a>). +With long axial field of view PET systems the RBF can be quantified from data acquired during +routine clinical myocardial perfusion PET/CT +(<a href="https://doi.org/10.1161/CIRCIMAGING.123.015324">Brown et al., 2023</a>).</p> <p><a href="https://doi.org/10.1038/ki.1993.340">Nitzsche et al (1993)</a> simplified the analysis further by using <a href="./model_mtga.html#patlak">Patlak plot</a> to estimate RBF, and validated diff --git a/content/target_tau-protein.html b/content/target_tau-protein.html index ffa042fbef7316537843b5450629bb93f8c07b6a..abd73a1ec4bbcf015fa9cfaafbfea0a6b24fe50c 100644 --- a/content/target_tau-protein.html +++ b/content/target_tau-protein.html @@ -1,7 +1,7 @@ --- title: Tau proteins author: Vesa Oikonen -updated_at: 2023-08-17 +updated_at: 2023-09-28 created_at: 2015-08-17 tags: - Tau protein @@ -202,7 +202,8 @@ high affinity (∼1.5 nM) and selectivity. <a href="./target_microtubules.html#MPC-6827">[<sup>11</sup>C]MPC-6827</a> is a promising PET radioligand for MT imaging (<a href="https://doi.org/10.1021/acs.jmedchem.8b00028">Kumar et al., 2018</a>; -<a href="https://doi.org/10.3390/molecules25102289">Damuka et al., 2020</a>).</p> +<a href="https://doi.org/10.3390/molecules25102289">Damuka et al., 2020</a>; +<a href="https://doi.org/10.1021/acschemneuro.3c00527">Bhoopal et al., 2023</a>).</p> <br>