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Commit ffa93023 authored by Vesa Oikonen's avatar Vesa Oikonen
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title: Analysis of [C-11]flumazenil
author: Vesa Oikonen
updated_at: 2020-01-01
updated_at: 2023-01-19
created_at: 2013-06-18
tags:
- GABA
......@@ -43,7 +43,10 @@ P-glycoprotein, at least in rodents
(<a href="https://doi.org/10.1186/2191-219X-2-12">Froklage et al., 2012</a>).
In humans, [<sup>11</sup>C]flumazenil is still useful for measuring the
GABA<sub>A</sub> receptor density
(<a href="https://doi.org/10.1177/0271678X15618219">Froklage et al., 2017</a>).</p>
(<a href="https://doi.org/10.1177/0271678X15618219">Froklage et al., 2017</a>).
GABA<sub>A</sub>Rs are very abundant in the cerebral cortex, and therefore [<sup>11</sup>C]flumazenil
gives a surrogate index of cortical thickness and neuronal density
(<a href="https://doi.org/10.1016/j.neuroimage.2010.11.015">la Fougère et al., 2011</a>).</p>
<h2>Compartmental model</h2>
......
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