Commit 99950c57 authored by Vesa Oikonen's avatar Vesa Oikonen
Browse files


parent c66ad77b
Pipeline #39089 passed with stages
in 1 minute and 34 seconds
......@@ -408,7 +408,7 @@ can also form nephrotoxic substances from originally harmless molecules.</p>
(<sup>99m</sup>Tc-MAG3) or <sup>99m</sup>Tc-DTPA and dynamic CT or SPECT is commonly used for
measurement of <a name="renal_function">renal function</a>. Renal function includes
<a href="#GFR">glomerular filtration</a> and <a href="#tubular">tubular function</a>.
In healthy kidneys, proximal tubules excrete <sup>99m</sup>Tc-MAG3 efficiently.
In healthy kidneys, proximal tubules excrete <sup>99m</sup>Tc-MAG3 efficiently via MRP2 and MRP4.
Initial increase (&sim; 2 min) in renal radioactivity provides an index of renal perfusion and
tubular uptake, and is proportional to GFR; the descending phase is used to assess the tubular
excretion. Fitting of the rising part provides renal <em>output efficiency</em> (<em>OE</em>)
Markdown is supported
0% or .
You are about to add 0 people to the discussion. Proceed with caution.
Finish editing this message first!
Please register or to comment