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Commit afe71c43 authored by Vesa Oikonen's avatar Vesa Oikonen
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<p>The pathways and brain regions involved in pain processing are relatively well-characterised,
and the neural mechanisms involved in pain processing can be studied using fMRI, PET, MEG, and EEG.
Pain-induced activation in the brain can be studied using <a href="./model_perfusion.html">perfusion</a>
PET radiotracers.
PET radiotracers.
Neural metabolism can be assessed with <a href="./analysis_18f-fdg.html">[<sup>18</sup>F]FDG</a> PET.
Neurotransmission of pain can be studied using PET radiopharmaceuticals that target
<a href="./target_adrenergic_system.html">noradrenaline</a>,
<a href="./target_serotonin.html">serotonin</a>,
......@@ -27,10 +28,9 @@ Additionally, <a href="./target_dopamine.html">dopamine system</a> is involved i
(<a href="https://doi.org/10.1016/j.ejphar.2004.07.024">Hagelberg et al., 2004</a>).
Pain is often linked to <a href="./target_inflammation.html">inflammation</a>, and
neuroinflammatory mechanisms link pain and <a href="./depression.html">depression</a>
(<a href="https://doi.org/10.1159/000435931">Burke et al., 2015</a>).</p>
(<a href="https://doi.org/10.1159/000435931">Burke et al., 2015</a>).
Inflammation in pain has been studied using <a href="./target_tspo.html">TSPO</a> radioligands.</p>
<p>Inflammation in chronic pain has been studied using <a href="./target_tspo.html">TSPO</a>
radioligands in humans.</p>
......@@ -60,4 +60,8 @@ doi: <a href="https://doi.org/10.1007/978-3-642-28753-4">10.1007/978-3-642-28753
Pain</em>. Springer, 2018.
doi: <a href="https://doi.org/10.1007/978-981-13-1756-9">10.1007/978-981-13-1756-9</a>.</p>
<p>Tung K-W, Behera D, Biswal S. Neuropathic pain mechanisms and imaging.
<em>Semin Musculoskelet Radiol.</em> 2015; 19: 103–111.
doi: <a href="https://doi.org/10.1055/s-0035-1547371">10.1055/s-0035-1547371</a>.</p>
<br>
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